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High dose chemotherapy definition

Web29 de mai. de 2024 · Introduction. The adjuvant anthracycline and taxane-based chemotherapies have been demonstrated to be superior to other regimens and can reduce mortality by about one-third in early breast cancer patients[1, 2].As an adjuvant treatment, dose-dense chemotherapy is designed to maintain high blood drug concentrations by … Web30 de jan. de 2024 · Myelosuppression, or bone marrow suppression, is defined as a decrease in the ability of the bone marrow to produce blood cells. This may result in a …

Myelosuppression: Definition, Causes, Types, and Treatment

WebThis definition further specifically includes all component parts of the procedure including, without limitation, the High Dose Chemotherapy and/or High Dose Radiotherapy. The physician must certify that alternative procedures, services, or courses of treatment would not be effective in the treatment of the Member's condition.1.4 High Dose … Web10 de abr. de 2024 · noun. : chemotherapy usually with high doses of anticancer drugs (as cisplatin or methotrexate) in the initial treatment especially of advanced cancers in order to make subsequent treatment (as surgery or radiotherapy) more effective. som city https://whimsyplay.com

Time-to-Treatment-Failure and Related Outcomes among 1000

Web7 de jul. de 2024 · Jo, J. C. et al. BEAC or BEAM high-dose chemotherapy followed by autologous stem cell transplantation in non-Hodgkin’s lymphoma patients: Comparative analysis of efficacy and toxicity. Web30 de mar. de 2024 · INTRODUCTION. Time-to-treatment-failure (TTF) is the interval from initiation of chemotherapy to its premature discontinuation. Since early discontinuation can occur due to various reasons – such as, cancer progression, adverse events, patient choice, or patient death – TTF can be influenced by factors unrelated to chemotherapy efficacy … WebNCI's Dictionary of Cancer Terms provides easy-to-understand definitions for words and phrases related to cancer and medicine. somc maternity ward

Chronic Myelogenous Leukemia Treatment (PDQ®)–Health ... - NCI

Category:How to Balance Treatment Risk, Benefit in Older Patients With …

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High dose chemotherapy definition

Chronic Myelogenous Leukemia Treatment (PDQ®)–Health ... - NCI

Web9 de abr. de 2024 · MRI or PET was recommended, to aid in target definition. The contour of GTV included primary tumor and metastatic lymph nodes. The PTV included 0–5 mm enlargement of GTV. The contour of the PTV cannot stretch into and overlap the margin of the gastrointestinal tract. The prescribed dose of PTV was 42.5–55.0 Gy, in 5–7 fractions. WebHigh-dose Chemotherapy and Stem Cell Transplant for Neuroblastoma. This type of treatment combines higher doses of chemotherapy (chemo) with a transplant to replace …

High dose chemotherapy definition

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Web16 de set. de 2024 · Definition. Chemotherapy is a group of medications used to treat cancer and sometimes other conditions. In cancer, chemotherapy—oftentimes simply … Webhigh-dose chemotherapy: Oncology The administration of chemotherapeutics in excess of BM toxicity; given the risk of aplastic anemia, HDC requires autologous BMT and use of …

WebAbstract. In experimental tumors, a steep dose-response curve has been demonstrated for chemosensitive malignancies. In clinical practice, increasing dose over the conventional … WebDefine High Dose Chemotherapy. means the use of a chemo-therapeutic agent or agents to treat cancer or cancer-like illness (with or without irradiation) in doses which …

Sequential high-dose chemotherapy is a chemotherapy regimen consisting of several (2 to 4) sequential monochemotherapies with only one chemotherapeutic agent per course. The idea behind this approach is that when using single-agent chemotherapy, the doctor can easily escalate the dose of the drug to the maximum tolerable dose by the patient, avoiding additive hematological toxicity from chemotherapeutic combinations, and thus improving efficacy. It is m… WebThe standard of care for fit multiple myeloma patients is to receive high-dose chemotherapy (HDT) with autologous stem cell rescue — otherwise known as autologous stem cell transplant (ASCT) — after completion of induction therapy. Autologous stem cell transplant can provide significant remission that is both long and deep, extending survival.

WebCandidates will have induction therapy followed by high-dose chemotherapy and a stem cell transplant. Induction therapy is usually given for several cycles. Induction therapy for multiple myeloma in people who are considered candidates for a stem cell transplant may include these drugs:

WebHigh dose chemotherapy with supportive therapy such as administration of hematopoietic growth factor, autologous bone marrow transplantation, or peripheral blood stem cell transfusion, was also reviewed. Some of these modality showed the suggestive correlation between these therapeutic intensification and the prolongation of survival rate. somc mathew dougmanWeb3 de mai. de 2024 · Adjuvant chemotherapy is used after other treatments to shrink remaining cancer cells. Consolidation chemotherapy is used after initial treatment to … som cms hospitalsWebVI. In your own simplified version, provide the definition and importance of the following principles: Efficacy: describes the maximum response that can be achieved with a drug. The effect of the drug is plotted against dose in a graph, to give the dose–response curve. Toxicity: refers to how poisonous or harmful a substance can be. somc netlearningWebThe term of dose intensity (DI) is used to define the drug dose delivered per time unit and is expressed as mg/m2 per week. A delay in the sequence of treatment cycles decreases … small business hubWeb12 de abr. de 2024 · Dose-dense chemotherapy is the practice of administering chemotherapy more often but at the same dosage of a typical chemotherapy regimen. … som coachingWeb8 de jan. de 2024 · Radiation therapy kills cancer cells or slows their growth by damaging their DNA. Radiation therapy (also called radiotherapy) is a cancer treatment that uses high doses of radiation to … som clothingWebHigh-dose chemotherapy has an extensive history in treating patients with metastatic disease. Again, results of Phase II studies were promising, with remarkable overall response rates of 73–100%, and up to 30% of patients maintaining complete remissions (CR) for … somc medical records dept