Irf7 mouse

Author: ehxd

August undefined, 2024

WebImmunohistochemistry-Paraffin: IRF7 Antibody (SC0617) [NBP2-67634] - Analysis of paraffin-embedded mouse liver tissue using anti-IRF7 antibody. Counter stained with hematoxylin. Flow Cytometry: IRF7 Antibody (SC0617) [NBP2-67634] - Analysis of Jurkat cells with IRF7 antibody at 1/50 dilution (red) compared with an unlabelled control (cells ... WebJan 18, 2024 · It has been proposed, based on studies of mouse Ifna4 and Ifna2 genes , that late-phase expression of IFNA genes is controlled by Irf7 binding to VRE-A/B, whereas early-phase expression is controlled by Irf3 binding to VRE-C. We show that for many IFNs (63%, 17/27) it is only IRF7 that binds to VRE-A/B, suggesting that late-phase expression ...

IRF7 - an overview ScienceDirect Topics

WebJan 10, 2024 · IRF7 is the key transcription factor which induces IFNα expression 9, leading to a second wave of type I IFN release. Since IFNα signals via the IFNAR this leads to a positive feedback loop that... WebPE Mouse anti-IRF-7 This SKU will be discontinuing June 2024. For additional support, contact your local applications specialist. Contact Us PE Mouse anti-IRF-7 Clone K40-321 … star trek picard 2x10 review

IRF7 Polyclonal Antibody (PA5-20281) - Thermo Fisher Scientific

WebOct 18, 2024 · Interferon regulatory factor 7 (IRF7) is the main transcriptional regulator of type I IFN, and it is crucial for the induction of IFNα/β and the type I IFN-dependent immune response. In this... WebJul 25, 2024 · By performing mass-spectrometry analysis of IRF3 and IRF7 isolated from cells treated with a SIRT1 inhibitor, we identified SIRT1-specific lysine-deacetylation sites and confirmed this result by... WebIRF7 play a major role in the innate immune pathway, interacting with the Toll-like receptor (TLR) adaptor proteins MyD88 and Tirp/TRAM and functioning as an intermediate TLR4 … star trek orion slave women

All Phenotypes Irf7 MGI Mouse - Mouse Genome …

The role of interferon regulatory factor 7 in the pathogenicity and ...

WebProduct Details. Partial mouse IRF7 recombinant protein (127-487a.a.) expressed in E. coli. Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide. The antibody was purified by affinity chromatography. The antibody solution should be stored undiluted between 2°C and 8°C. WebUsing the International Mouse Strain Resource Mouse lines carrying: Irf7 tm1Ttg mutation (2 available); any Irf7 mutation (16 available) ♀ phenotype observed in females pet friendly hotels near weedsport txWebApr 7, 2005 · Consistently, Irf7-/- mice are more vulnerable than Myd88-/- mice to viral infection, and this correlates with a marked decrease in serum IFN levels, indicating the … star trek orion species

"WebJul 14, 2016 · IRF3-5D, an active form of IRF3, and IRF7Δ247–467, a constitutively active form of IRF7 were constructed as previously described using pFLAG-IRF3, and pFLAG-IRF7 plasmids as templates 38,39,40 ... " - Irf7 mouse

Irf7 mouse

DNA-binding landscape of IRF3, IRF5 and IRF7 dimers: …

WebMay 21, 2024 · By combining DNA microarray and genomic data analyses to predict DNA binding motifs, we identified the transcription factor Interferon Regulatory Factor 7 (IRF7) as a possible regulator of genes related to adipocyte hypertrophy. WebJul 7, 2024 · Buy GameSir F7 Claw PUBG Controller for iPad/Tablet, Six Finger Game Joystick Trigger Handle Aim Button L1R1 L2R2 Shooter Gamepad, Plug and Play Gaming …

Did you know?

WebIRF7 play a major role in the innate immune pathway, interacting with the Toll-like receptor (TLR) adaptor proteins MyD88 and Tirp/TRAM and functioning as an intermediate TLR4 and TLR9 signaling. There are at least four differentially spliced isoforms of IRF7, although their function has not been clearly established. For Research Use Only. WebMar 7, 2024 · Here we used MLL-AF9-induced acute myeloid leukemia (AML) mouse models with IRF7 knockout or overexpression and xenograft mouse models to explore the …

WebJun 19, 2024 · To elucidate pDC immunomodulatory functions, we developed a mouse model in which IRF7 signaling is restricted to pDC. Despite undetectable levels of IFN-I protein, pDC-restricted IRF7 signaling controlled both viruses and was sufficient to protect mice from lethal CHIKV infection. Early pDC IRF7-signaling resulted in amplification of … WebApr 13, 2024 · RNA sequencing analysis of IRF7 CRISPRa and CRISPRi- DF-1 cells revealed the specificity of CRISPRa and CRISPRi-based targeted transcriptional regulation with minimal off-target effects. ... Cox, T.; Melvin, D.; Wang, X.; Bradley, A.; Liu, P. Chromosomal transposition of PiggyBac in mouse embryonic stem cells. Proc. Natl. Acad. Sci. USA …

IRF7 encodes interferon regulatory factor 7, a member of the interferon regulatory transcription factor (IRF) family. IRF7 has been shown to play a role in the transcriptional activation of virus-inducible cellular genes, including the type I interferon genes. In particular, IRF7 regulates many interferon-alpha genes. Constitutive expression of IRF7 is largely restricted to lymphoid tissue, largely plasmacytoid dendritic cells, whereas IRF7 is inducible in many tissues. Multiple IRF7 tra… WebIRF7 play a major role in the innate immune pathway, interacting with the Toll-like receptor (TLR) adaptor proteins MyD88 and Tirp/TRAM and functioning as an intermediate TLR4 and TLR9 signaling. There are at …

WebInterferon regulatory receptor 7 (IRF7) is a transcription factor involved in the activation of the type I interferon (IFN) response upon pathogenic infection [3-4]. IRF7 has been implicated downstream of several pattern recognition receptors (PRRs), including TLRs, RLRs, and DNA sensors [2].

WebNov 30, 2024 · IRF7 could regulate the transcription of Usp25 in mouse embryonic fibroblast (MEFs) and BM-derived dendritic cells (BMDCs) in response to viral infection or LPS. 42 It was reported that Usp25 binds with the promoter of Sox2 that played an important role in the pluripotency of embryonic stem cells development. 43, 44 Whether Usp25 is a potential ... star trek ornaments by yearWebPrimePCR™ PreAmp for SYBR® Green Assay: Irf7, Mouse Reaction: 400 reactions Gene-specific PCR primers for the unbiased preamplification of small quantities of cDNA for subsequent use in downstream gene expression analysis. pet friendly hotels near waco txWebMouse Immunogen Partial IRF7 recombinant protein (127-503 a.a.) Formulation Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA) … star trek phase ii castWebMouse Antibody Type Monoclonal Host Species Rat Immunogen Partial mouse IRF7 recombinant protein (127-487a.a.) expressed in E. coli. Formulation Phosphate-buffered … pet friendly hotels new albany indianaWebRestoration of IRF7 in tumor cells isolated from metastatic mouse primary mammary tumors restored the ability to secrete IFN and reduced the metastatic burden in a breast … star trek picard kirk thatcherWebIRF7 Antibody (PA5-20281) in IHC Immunohistochemistry of IRF7 in mouse spleen tissue with IRF7 Polyclonal Antibody (Product # PA5-20281) at 5 µg/mL. Product Details Product Specific Information A suggested positive control is 293 cell lysate. PA5-20281 can be used with blocking peptide PEP-0415. Target Information star trek phaser imageWebIrf7 Name interferon regulatory factor 7 Feature Type protein coding gene IDs MGI:1859212 NCBI Gene: 54123 Alliance gene page Transcription Start Sites 17 TSS Location & Maps … star trek picard five imposters