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Procathepsin b

Webb摘要 目的探讨组织蛋白酶B(CatB)表达对结直肠癌细胞黏附和侵袭行为的影响。 方法选用人结肠癌细胞系LoVo和人直肠癌细胞系HR-8348,将含CatB全长cDNA的质粒pcDNA3CatB分别转染LoVo和HR-8348细胞。 Webb29 apr. 1994 · Maturation of human procathepsin B. Proenzyme activation and proteolytic processing of the precursor to the mature proteinase, in vitro, are primarily unimolecular …

THE OF Vol. 267, No. 22, Issue of 5, pp. 15993-15999,1992 The for …

Webb10 apr. 2011 · Procathepsin B is shuttled to the Golgi apparatus where further modification of the oligosaccharides to unique high-mannose carbohydrates occurs (Takahashi et al. 1984). Phosphorylation of the mannose residues directs the enzyme to the endosomal/lysosomal compartment via the mannose-6-phosphate receptor pathway. WebbThe purified recombinant proenzyme is activated in vitro under acidic conditions resulting in rapid conversion into the mature form of the proteinase. Activation as well as … cheap vinyl sheets for crafting https://whimsyplay.com

Competition between plasminogen and procathepsin B as a probe …

WebbDetect Cathepsin B using this rabbit polyclonal Anti-Cathepsin B Antibody, Cat. No. 06-480-I. It has been tested in Immunohistochemistry (Paraffin) and Western Blotting. Anti … Webb7 aug. 1996 · The aim of our study was to identify changes in secreted procathepsin B levels in a model of the human colorectal adenoma to carcinoma sequence and to … Webb15 okt. 1996 · Cathepsin L is a member of the papain superfamily of cysteine proteases and, like many other proteases, it is synthesized as an inactive proenzyme. Its prosegment shows little homology to that of procathepsin B, whose structure, the first for a cysteine protease proenzyme, has been determined recently. cyclestyle book

Glycosaminoglycans facilitate procathepsin B activation through ...

Category:The Role of Cathepsin B in Ischemia-Reperfusion Injury After Stroke

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Procathepsin b

Human Pro-Cathepsin B ELISA Kit - Invitrogen - Thermo Fisher …

Webbof rat procathepsin B, residues 1p–62p, represented in one-letter code, followed by the beginning of the mature sequence (italics). Secondary structural elements are marked above the sequence. (b) Stereoview of the Ca trace of procathepsin B. The prosegment and C-terminal extension are shown in thicker lines. Catalytic residues Ser29 (Cys ... WebbHuman Pro-cathepsin B ELISA KIT 经营进口胎牛血清、细胞因子、ELISA试剂盒、细胞、抗体、生物试剂、耗材、培养基、一抗、二抗、其产品吸附均匀，吸附性好，空白值低，孔底透明度高，代做ELISA实验等。 【生物分子】 抗生素/抗真菌素 维生素 氨基酸 核苷酸 脂 糖类 白三烯 前列腺素 药物结合物 抗氧化剂 ...

Procathepsin b

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Webb1 mars 1992 · The lysosomal cysteine proteinase cathepsin B is synthesized in cultured human hepatoma HepG2 cells as an inactive 44 kDa precursor and subsequently … Webb1 okt. 1996 · Its prosegment shows little homology to that of procathepsin B, whose structure, the first for a cysteine protease proenzyme, has been determined recently. We report here the 3-D structure of a mutant of human procathepsin L determined at 2.2 A resolution, describe the mode of binding employed by the prosegment and discuss the …

WebbInterestingly, cathepsin B sorting to lysosomes was not inhibited by NH(4)Cl treatment and about 90% of the intracellular procathepsin B initially phosphorylated was secreted into the medium without being dephosphorylated intracellularly, and did not bind significantly to cation-independent-Man 6-P receptor, suggesting the failure of Man 6-P-dependent … Webb17 aug. 1999 · Its prosegment shows little homology to that of procathepsin B, whose structure, the first for a cysteine protease proenzyme, has been determined recently ... Macromolecules Find similar proteins by: (by identity cutoff) 3D Structure Small Molecules Experimental Data & Validation Experimental Data Method: X-RAY DIFFRACTION …

Webb1 juli 2000 · Treatment of intracellular 35 S-label-ed procathepsin B with a molecular mass of 39-kDa with cathepsin D resulted in the production of the 31-kDa intermediate form, but the 32 P-label incorporated into procathepsin B … WebbCathepsin B is a cysteine protease, found in the lysosome of normal cells and tissues. [ 1] Cathepsin B active human is encoded by the gene CTSB, located on human chromosome 8p23.1. [ 2] Application Active human cathepsin B is useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling.

Webb5 aug. 2013 · In the Procathepsin B study, serum samples of healthy women (n=32) aged 18-40 years (n=14), 41-55 years (n=10) and 56-80 (n=8) years were used as controls. …

Webb公告提醒：爱必信所有产品和服务仅用于科学研究，不用于临床应用及其他用途提供产品和服务（也不为任何个人提供产品和服务）! 试剂描述： 产品名称：4-肼基苯甲酸肼 产品别名： CAS号：93574-69-7 英文别名：4-肼基苯甲酸肼 分子量：166.18 分子式：C7H10N4O cycle surgery bishops squarecheap vinyl shed windowsWebb15 nov. 1996 · The tissue plasminogen activator (tPA) was found to activate in vitro the procathepsin B purified from malignant ascitic fluids. This activation was time and dose … cheap vinyl siding canadahttp://yuxiqbs.cqvip.com/Qikan/Article/Detail?id=27319169 cheap vinyl rectangle tableclothsWebb14 jan. 2009 · Cathepsin B (EC 3.4.22.1) is one of the most abundant and thoroughly studied. It plays an important role in nonselective protein degradation inside lysosomes, … cycle suffolkWebb1 maj 1997 · Cathepsin B is a lysosomal cysteine protease of the papain family. It functions in intracellular protein catabolism and in certain situations may also be … cycle surgery chertseyWebb开馆时间：周一至周日7:00-22:30 周五 7:00-12:00; 我的图书馆 cycle superhighways map